10H8 anti Alpha-gal Human IgE Monoclonal Antibody (E-10H8)

Certificate of Analysis

Antibody Clone:

10H8-IgE

Vial:

Orange Cap; 200µl

Origin:

Monoclonal antibody derived from a patient allergic to red meat.

Specificity:

Alpha-gal (galactose-α-1,3-galactose).

Allergen:

Natural Alpha-gal (product code NA-AGAL-1)

IgE Concentration:

50,000 IU/mL (+/- 20%) based on ImmunoCAP using WHO International Standard for Immunoglobulin E (IgE) (NIBSC code 11/234)

Quantity:

10,000 IU in 0.2mL (1.0 IU = ~2.4ng IgE)

Formulation:

In phosphate buffered saline, pH 7.4 and 0.05% Tween-20. 0.22µm filtered, preservative free.

Storage:

Maintain at -20°C for up to 12 months. Avoid repeated freeze-thaw cycles. Store product undiluted. No stability data available. 

Application Note:

Not suitable for western blot

Product Resources:

References:

Khatri K. et al., Human IgE monoclonal antibody recognition of mite
allergen Der p 2 defines structural basis of an epitope for IgE cross-
linking and anaphylaxis in vivo, PNAS Nexus, 2022; 0:1-0.

Wurth, M.A. et al., Human IgE mAbs define variability in commercial
Aspergillus extract allergen composition, JCI Insight. 2018;3
(20):e123387.

Bazaral, M. and Hamburger, R.N., Standardization and stability of
immunoglobulin E, J Allergy Clin Immunol 1972; 49:189-191. PMID
4622102.

For research and in vitro diagnostic use only: Not for human in vivo or therapeutic use.