2G1 anti Der p 2 Human IgE Monoclonal Antibody (E-2G1)
Certificate of Analysis
Antibody Clone: 2G1-IgE
Vial: Orange Cap; 200µl
Origin: Monoclonal antibody derived from a patient allergic to house dust mite.
Specificity: Der p 2, Dermatophagoides pteronyssinus Group 2 allergen.
Allergen: Natural Der p 2 (NA-DP2-1)
IgE Concentration: 50,000 IU/mL based on ImmunoCAP using WHO International Standard Immunoglobulin E (IgE), human serum (NIBSC code 11/234)
Quantity: 10,000 IU in 0.2mL (1.0 IU = ~2.4ng IgE)
Formulation: In phosphate buffered saline, pH 7.4 and 0.05% Tween-20. 0.22µm filtered, preservative free.
Storage: Maintain at -70°C for up to 6 months. Avoid repeated freeze-thaw cycles. Store product undiluted.
References:
- Khatri K. et al., Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo, PNAS Nexus, 2022; 0:1-0.
- Wurth, M.A. et al., Human IgE mAbs define variability in commercial Aspergillus extract allergen composition, JCI Insight. 2018;3 (20):e123387.
- Bazaral, M. and Hamburger, R.N., Standardization and stability of Immunoglobulin E, J Allergy Clin Immunol 1972; 49:189-191. PMID 4622102.
For research and in vitro diagnostic use only: Not for human in vivo or therapeutic use.
