Mouse anti Der p 2/human IgE (2B12-IgE) (CH-1)

Certificate of Analysis

Monoclonal Antibody: 2B12-IgE

Vial: Purple Cap; 500µl

Immunogen: Der p 2

Isotype: Human IgE

Specificity: Binds to species specific epitope present on Dermatophagoides pteronyssinus allergen, Der p 2.

Purification: Kappa light chains and one VH domain of murine anti-Der p 2 monoclonal antibody 2B12 B3 co-expressed with heavy chain constant domains of human IgE in a hybridoma cell line. Culture supernate from 2B12-IgE hybridoma cell line.

Concentration: 2550 IU IgE /ml (substandardized to WHO IgE 75/502)

Storage: Store at 4°C

Product Resources: CH-1 Certificate of Analysis

For Research Use Only: Not for Diagnostic or Therapeutic Use

References:
Schuurman J, Perdok GL, Lourens TE, Parren PWHI, Chapman MD, Aalberse RC. The production of a mouse/human chimeric IgE monoclonal antibody to the house dust mite allergen Der p 2 and its use for the absolute quantification of allergen specific IgE. J Allergy Clin Immunol 99:545-550, 1997.