Recombinant Human Rhinovirus 16 VP1 (HRV-VP1)

Recombinant Protein: Human Rhinovirus 16 VP1 (Viral Protein 1, aa 565-853)

Unit: 50µg

Source: E.coli

Mol. Wt: 33 kD

Purification: Purified from E.coli by multi-step chromatography.

Concentration: See product insert.

Formulation: Preservative and carrier-free in 0.3M NaCl, 20mM Tris, 0.5 M Arginine, pH 8.0. Filtered through 0.22µm filter.

Storage: Store at -20ºC. Avoid repeated freeze-thaw cycles.

Notes: (1) HRV 16 VP1 has a C-terminal 8xHis-tag. (2) HRV VP1 solubility requires Tris buffer and Arginine

Product Resources: Human Rhinovirus 16 VP1 Certificate of Analysis

For research and commercial use in vitro: not for human in vivo or therapeutic use.

References:

1. Bochkov YA and Gern JE. Rhinoviruses and Their Receptors: Implications for Allergic Disease. Curr Allergy Asthma Rep. 2016 Apr;16(4):30.
2. Coleman L et al. Rhinovirus-induced asthma exacerbations and risk populations. Curr Opin Allergy Clin Immunol. 2016 Apr;16(2):179-85.
3. Hadfield AT et al. The refined structure of human rhinovirus 16 at 2.15 A resolution: implications for the viral life cycle. Structure. 1997 Mar 15;5(3):427-41.
4. Agah S. et al. An efficient approach for recombinant expression and purification of Rhinovirus 16 (HRV-16) capsid proteins in Escherichia coli. J. Allerg. Clin. Immnol.2018, 144(2): AB113