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Natural Shrimp Tropomyosin (NA-STM-1)

  • Natural Shrimp Tropomyosin (NA-STM-1)
Allergen: NA-STM-1, shrimp
Unit: 250µg
Source: Carolina Shrimp (see Note 3 for species information)
Mol. Wt: 36 kD
Purification: From boiled shrimp extract by affinity chromatography. 
Purity on silver stained SDS-PAGE >95%. 
Concentration: See product insert.
Formulation:

Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Sterile filtered.

Storage: Store at -20ºC
Notes:
  1. Additional bands below 36kD represent tropomyosin fragments.
  2. Avoid repeated Freeze/Thaw cycles.
  3. There are generally two species, the white (L.setiferus) and brown (F. aztecus) shrimp that overlap in seasons in the Carolina waters. Pink shrimp (F. duorarum) also occur, especially in North Carolina catches. Because of the overlap of three different species, we cannot specify the species, most likely it is a mixture.
Product Resources: NA-STM-1 CoA

Focus on... Shrimp Tropomyosin

Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use.
References:  
  1. Shanti KN, Martin BM, Nagpal S, Metcalfe DD, Subba Rao PV. Identification of tropomyosin as the major shrimp allergen and characterization of its IgE-binding epitopes. J Immunol. 151(10):5354-5363. 1993
  2. Daul CB, Slattery M, Reese G, Lehrer SB. Identification of the major brown shrimp (Penaeus aztecus) allergen as the muscle protein tropomyosin. Int Arch Allergy Immunol. 105(1):49-55. 1994
  3. Jeoung BJ, Reese G, Hauck P, Oliver JB, Daul CB, Lehrer SB. Quantification of the major brown shrimp allergen Pen a 1 (tropomyosin) by a monoclonal antibody-based sandwich ELISA. J Allergy Clin Immunol. 100(2):229-234. 1997
  4. Santos AB, Rocha GM, Oliver C, Ferriani VPL, Lima RC, Palma MS, Sales VSF, Aalberse RC, Chapman MD, Arruda LK. Cross-reactive IgE antibody responses to tropomyosins from Ascaris lumbricoides and cockroach. J Allergy Clin Immunol 2008; 121(4):1040-1046
 
File Name Size Added Link
NA-STM_CoA 188.95KB 20/05/2014 Download
Natural Shrimp Tropomyosin Certificate of Analysis
  • Product Code: NA-STM-1
  • Availability: In Stock
  • $625.00

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