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Allergen: |
nCor a 9 (Corylus avellana allergen 9), hazelnut |
Unit: | 250µg |
Source: | 11S globulin from hazelnut. |
Mol. Wt: | Multiple subunits ranging from 30 to 59 kD |
Purification: |
Purified from hazelnut extract by multi-step HPLC. |
Concentration: |
See product insert. |
Formulation: |
Preservative and carrier-free in 1M NaCl, PBS pH 7.40. Filtered through 0.22µm filter. |
Storage: | Store at -20ºC. Avoid repeated freeze-thaw cycles |
Notes: |
(1) 11S globulins are synthesized as single peptide chain precursors that are cleaved post-translationally. (2) Solubility of Cor a 9 is dependent on the presence of at least 1M NaCl. |
Genbank: | |
PDB: | |
Product Resources: | |
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. | |
References: |
|
1. Beyer K et al. Identification of an11S globulin as a major hazelnut food allergen in hazelnut-induced systemic reactions. J Allergy Clin Immunol. 2002;110(3):517-23. 2. Guo Fet al. Purification and crystallization of Cor a 9, a major hazelnut allergen. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009;65:42-6. 3. Masthoff LJ et al. Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults. J Allergy Clin Immunol. 2013;132(2):393-9 |
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File Name | Size | Added | Link |
NA-CA9_CoA | 250.22KB | 17/03/2017 | Download |
Natural Cor a 9 Certificate of Analysis |
Tags: food allergen, hazelnut, Cor a 1, purified allergen,