10H8 anti Alpha-gal Human IgE Monoclonal Antibody (E-10H8)
Certificate of Analysis
Antibody Clone: 10H8-IgE
Vial: Orange Cap; 200µl
Origin: Monoclonal antibody derived from a patient allergic to red meat.
Specificity: Alpha-gal (galactose-α-1,3-galactose).
Allergen: Natural Alpha-gal (product code AGAL-1)
IgE Concentration: 50,000 IU/mL (+/- 20%) based on ImmunoCAP using WHO International Standard for Immunoglobulin E (IgE) (NIBSC code 11/234)
Quantity: 10,000 IU in 0.2mL (1.0 IU = ~2.4ng IgE)
Formulation: In phosphate buffered saline, pH 7.4 and 0.05% Tween-20. 0.22µm filtered, preservative free.
Storage: Maintain at -70°C for up to 6 months. Avoid repeated freeze-thaw cycles. Store product undiluted.
Application Note: Not suitable for western blot
References:
- Khatri K. et al., Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo, PNAS Nexus, 2022; 0:1-0.
- Wurth, M.A. et al., Human IgE mAbs define variability in commercial Aspergillus extract allergen composition, JCI Insight. 2018;3 (20):e123387.
- Bazaral, M. and Hamburger, R.N., Standardization and stability of immunoglobulin E, J Allergy Clin Immunol 1972; 49:189-191. PMID 4622102.
For research and in vitro diagnostic use only: Not for human in vivo or therapeutic use.
