17E2 anti Fel d 1 Human IgE Monoclonal Antibody (E-17E2)

Certificate of Analysis

Antibody Clone: 17E2-IgE

Vial: Orange Cap; 200µl

Origin: Highly purified monoclonal antibody derived from IgE-producing cell lines.

Specificity: Fel d 1, Felis domesticus allergen.

Allergen: Natural Fel d 1 (product code NA-FD1-1)

Specific IgE Concentration: 50,000 IU/mL based on ImmunoCAP using WHO International Standard Immunoglobulin E (IgE), human serum (NIBSC code 11/234)

Quantity: 10,000 IU in 0.2mL (1.0 IU = ~2.4ng IgE)

Formulation: In phosphate buffered saline, pH 7.4 and 0.05% Tween-20. 0.22µm filtered, preservative free.

Storage: Maintain at -70°C for up to 6 months. Avoid repeated freeze-thaw cycles. Store product undiluted.

References:

1. Khatri K. et al., Human IgE monoclonal antibody recognition of mite allergen Der p 2 defines structural basis of an epitope for IgE cross-linking and anaphylaxis in vivo, PNAS Nexus, 2022; 0:1-0.
2. Wurth, M.A. et al., Human IgE mAbs define variability in commercial Aspergillus extract allergen composition, JCI Insight. 2018;3 (20):e123387.
3. Bazaral, M. and Hamburger, R.N., Standardization and stability of immunoglobulin E, J Allergy Clin Immunol 1972; 49:189-191. PMID 4622102.

For research and in vitro diagnostic use only: Not for human in vivo or therapeutic use.