Recombinant Ves v 5 (RP-VV5-1)

Allergen:	rVes v 5.0101 (Vespula vulgaris allergen 5.0101), Yellow jacket, wasp
Unit:	250µg
Source:	Pichia pastoris
Mol. Wt:	24kD
Purification:	Purified from Pichia pastoris culture by multi-step chromatography. Purity >95% by SDS-PAGE.
Concentration:	See product insert.
Formulation:	Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Filtered through 0.22µm filter.
Storage:	Store at -20ºC. Avoid repeated freeze-thaw cycles.
Notes:	(1) rVes v 5 has a N-terminal 6xHis-tag
Product Resources:	Recombinant Ves v 5 Certificate of Analysis
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
Ollert M, Blank S. Anaphylaxis to Insect Venom Allergens: Role of Molecular Diagnostics. Curr Allergy Asthma. 2015, 15:26.
Mȕller U, Schmid-Grendelmeier P, Hausmann O, Helbling A. IgE to Recombinant Allergens Api m 1, Ves v 1, and Ves v 5 Distinguish Double Sensitization from Crossreaction in Venom Allergy. Allergy. 2012 Aug;67(8):1069-73.
Ebo DG, Faber M, Sabato V, Leysin J, Bridts CH, De Clerck LS. Component-resolved Diagnosis of Wasp (Yellow Jacket) Venom Allergy. Clinical & Experimental Allergy 2012;43:255-261. Suck R, Weber B, Kahlert H, Hagen S, Cromwell O, Fiebig H. Purification and Immunobiochemical Characterization of Folding Variants of the Recombinant Major Wasp Allergen Ves v 5 (Antigen 5). Int Arch Allergy Immunol 2000;121:284-291.

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