Recombinant Bos d 2 (RP-BD2-1)

Allergen: rBos d 2 (Bos domesticus allergen 2.0101), cow

Unit: 250µg

Source: P. pastoris

Mol. Wt: 18 kD

Purification: Purified from Pichia pastoris culture by multi-step chromatography. Purity >95% by SDS-PAGE. (See Panel).

Concentration: See Product Insert.

Formulation: Preservative and carrier-free in phosphate buffered saline, pH 7.4. Filtered through 0.22 µm filter.

Storage: Store at -20ºC.

Notes: Not tested for endotoxin.

Product Resources: Recombinant Bos d 2 Certificate of Analysis

Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:

1. Kauppinen A, Peräsaari J, Taivainen A, Kinnunen T, Saarelainen S, Rytkönen-Nissinen M, Jeal H, Jones M, Virtanen T. Association of HLA class II alleles with sensitization to cow dander Bos d 2, an important occupational allergen. Immunobiology. 2012 Jan; 217(1):8-12.
2. Saarelainen SA, Kinnunen TT, Buhot C, Närvänen AT, Kauppinen AK, Rytkönen-Nissinen MA, Maillere B, Virtanen TI. Immunotherapeutic potential of the immunodominant T-cell epitope of lipocalin allergen Bos d 2 and its analogues. Immunology. 2008 Mar;123(3):358-66.
3. Rouvinen J, Rautiainen J, Virtanen T, Zeiler T, Kauppinen J, Taivainen A, Mäntyjärvi R. Probing the molecular basis of Allergy: Three-dimensional structure of the bovine lipocalin allergen Bos d 2. The Journal of Biological Chemistry 1999;274(4):2337-43.