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Natural Amb a 1 (NA-AAR1-1)

  • Natural Amb a 1 (NA-AAR1-1)
Allergen: nAmb a 1 (Ambrosia artemisiifolia allergen 1),Short ragweed
Unit: 250 µg
Source: Short ragweed pollen (Ambrosia artemisiifolia)
Mol. Wt: 38-40 kDa
Purification:

From delipidated short ragweed extract by multi-step chromatography.

Purity > 95 % by silver stained SDS-PAGE
Concentration: See product insert.
Formulation:

Preservative-free and carrier-free in phosphate buffered
saline, pH 7.4. Filtered through 0.22µ filter.
Storage: Store at -20ºC
Notes: Natural Amb a 1 undergoes proteolysis during purification and is cleaved into two non-covalently associated chains of ~25kD (α-chain) and 16kD (β-chain).
PDB:  
Product Resources: Natural Amb a 1 Certificate of Analysis
Allergens are provided for research and commercial use in vitro: Not for human in vivo or therapeutic use.
References:  
  1. Jahn-Schmid B, Wopfner N, Hubinger G, Asero R, Ebner C, Ferreira F, Bohle B. The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements. J Allergy Clin Immunol 2010; 126(5):1068-1071.
  2. Rafnar T, Griffith IJ, Kuo MC, Bond JF, Rogers BL, Klapper DG. Cloning of Amb a I (antigen E), the major allergen family of short ragweed pollen. J Biol Chem 1991; 266(2):1229-1236.
  3. Wopfner N, Bauer R, Thalhamer J, Ferreira F, Chapman M. Immunologic analysis of monoclonal and immunoglobulin E antibody epitopes on natural and recombinant Amb a 1. Clin Exp Allergy 2008; 38(1):219-226.
  4. King TP, Norman PS. Isolation of allergens from ragweed pollen. Biochemistry 1962; 1:709–720.
File Name Size Added Link
NA-AAR1_CoA 193.75KB 20/05/2014 Download
Natural Amb a 1 Certificate of Analysis
  • Product Code: NA-AAR1-1
  • Availability: In Stock

  • $665.00

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