Recombinant Cor a 14 (RP-CA14-1)

Allergen:	rCor a 14 (Corylus avellana allergen 14.0101), hazelnut
Unit:	250µg
Source:	Pichia pastoris
Mol. Wt:	15 kD
Purification:	Purified from Pichia pastoris culture by His-Trap chromatography. Purity > 95 % by silver stained SDS-PAGE, run under reducing conditions.
Concentration:	See product insert.
Formulation:	Preservative and carrier-free in 1X PBS, 360 mM NaCl, pH 7.4. Filtered through 0.22µm filter.
Storage:	Store at -20ºC.
Notes:	(1) rCor a 14 has a C-terminal 6xHis-tag. (2) Avoid repeated Freeze/Thaw cycles.
Genbank:
PDB:
Product Resources:	Recombinant Cor a 14 Certificate of Analysis
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
Garino C et al. Isolation, cloning, and characterization of the 2S albumin: a new allergen from hazelnut. Mol Nutr Food Res 2010; 54(9):1257-65. Masthoff LJ et al. Sensitization to Cor a 9 and Cor a 14 is highly specific for a hazelnut allergy with objective symptoms in Dutch children and adults. J Allergy Clin Immunol 2013;132(2):393-9. Faber MA. Cor a 14: missing link in the molecular diagnosis of hazelnut allergy? Int Arch Allergy Immunol. 2014;164(3):200-6. Pfeifer S et al. Cor a 14, the allergenic 2S albumin from hazelnut, is highly thermostable and resistant to gastrointestinal digestion. Mol Nutr Food Res. 2015 Oct;59(10):2077-86.