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Recombinant Bet v 1 (RP-BV1-1)
| Allergen: | rBet v 1 (Betula pendula allergen 1.0101), silver birch |
| Unit: | 250µg |
| Source: | Pichia pastoris |
| Mol. Wt: | 18kD |
| Purification: |
Purified from Pichia pastoris culture by HPLC gel filtration. Purity >95 % by silver stained SDS-PAGE |
| Concentration: |
See product insert. |
| Formulation: |
Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Steriled filtered. |
| Storage: | Store at -20ºC. |
| Notes: |
Glycosylation site N82 mutated (N82Q). Avoid repeated freeze-thaw cycles
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| Genbank: | |
| PDB: | |
| Product Resources: | Recombinant Bet v 1 Certificate of Analysis |
| Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. | |
| References: | |
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Batard, T. et al: Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy. Int Arch Allergy Immunol 2005, 136 (3), 239-249. |
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Breiteneder, H.et al: The gene coding for the major birch pollen allergen Bet v 1, is highly homologous to a pea disease resistance response gene. EMBO J 1989, 8 (7), 1935-1938. |
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Spangfort, M. D.et al: Dominating IgE-binding epitope of Bet v 1, the major allergen of birch pollen, characterized by X-ray crystallography and site-directed mutagenesis. J Immunol 2003, 171 (6), 3084-3090. |
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Swoboda, I.et al: Isoforms of Bet v 1, the major birch pollen allergen, analyzed by liquid chromatography, mass spectrometry, and cDNA cloning. J Biol Chem 1995, 270 (6), 2607-2613. |
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S. Vieths et al.: Establishment of recombinant major allergens Bet v 1 and Phl p 5a as Ph. Eur. Reference standards and validation of ELISA methods for their measurement. Pharmeuropa Bio & SN 2012; 118-13. |
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| File Name | Size | Added | Link |
| RP-BV1_CoA | 43.66KB | 16/07/2014 | Download |
| Recombinant Bet v 1 Certificate of Analysis | |||
- Product Code: RP-BV1-1
- Availability: In Stock
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$665.00
