Natural Bos d 5 (NA-BD5-1)

| Allergen: |
nBos d 5 (β-Lactoglobulin), Cow's milk |
| Unit: |
250µg |
| Source: |
Partially purified Bovine milk |
| Mol. Wt: |
18 kD |
| Purification: |
Column chromatography. Purity on silver stained SDS-PAGE >95%.
|
| Concentration: |
See product insert. Based on OD 280 nm. Extinction coefficient = 0.94
|
| Formulation: |
Preservative and carrier-free in endotoxin free phosphate buffered saline, pH 7.4. Filtered through 0.22µm filter.
|
| Storage: |
Store at -20ºC |
| Notes: |
β -Lactoglobulin runs at 18 kD with dimer at 36 kD on non-reducing SDS-PAGE. |
| PDB: |
|
| Product Resources: |
Natural Bos d 5 Certificate of Analysis
|
| Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use. |
| References: |
|
- Alexander LJ, Hayes G, Pearse MJ, Beattie CW, Stewart AF, et al. Complete sequence of the bovine beta-lactoglobulin cDNA. Nucleic Acids Res 1989;17(16):6739.
- Roth-Walter F, Pacios LF, Gomez-Casado C, Hofstetter G, Roth GA, et al. The major cow milk allergen Bos d 5 manipulates T-helper cells depending on its load with siderophore-bound iron. PLoS One. 2014; 9(8): e104803.
- Luyt D, Ball H, Makwana N, Green MR, Bravin K, et al. BSACI Guideline for the Diagnosis and Management of Cow's Milk Allergy. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology. 2014.
- Fiocchi A, Bouygue GR, Albarini M, Restani P. Molecular diagnosis of cow’s milk allergy. Curr Opin Allergy Clin Immunol. 2011 Jun;11(3):216-21.
- Kuwata K, Hoshino M, Forge V, Era S, Batt CA, Goto Y. Solution structure and dynamics of bovine beta-lactoglobulin A. Protein Sci. 1999 Nov;8(11):2541-5.
|
| File Name |
Size |
Added |
Link |
| NA-BD5_CoA |
221.79KB |
23/03/2015 |
Download |
| Natural Bos d 5 Certificate of Analysis |
- Product Code: NA-BD5-1
- Availability: In Stock
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Tags:
milk allergen,
food allergen,
bos d 5,
β-Lactoglobulin,
milk,