Natural Bos d 5 (NA-BD5-1)
		
        
		          
                        
 
                                  
                    
          
            
	
		
			| Allergen: | 
			nBos d 5 (β-Lactoglobulin), Cow's milk | 
		
		
			| Unit: | 
			250µg | 
		
		
			| Source:  | 
			Partially purified Bovine milk  | 
		
		
			| Mol. Wt: | 
			18 kD | 
		
		
			| Purification: | 
			
			 Column chromatography. Purity on silver stained SDS-PAGE >95%. 
			 | 
		
		
			| Concentration: | 
			
			 See product insert.  Based on OD 280 nm. Extinction coefficient = 0.94 
			 | 
		
		
			| Formulation: | 
			
			 Preservative and carrier-free in endotoxin free phosphate buffered saline, pH 7.4. Filtered through 0.22µm filter. 
			 | 
		
		
			| Storage: | 
			Store at -20ºC | 
		
		
			| Notes: | 
			β -Lactoglobulin runs at 18 kD with dimer at 36 kD on non-reducing SDS-PAGE. | 
		
		
			| PDB: | 
			  | 
		
		
			| Product Resources: | 
			
			 Natural Bos d 5 Certificate of Analysis 
			 | 
		
		
			| Allergens are provided for research and commercial use in vitro:  not for human in vivo or therapeutic use. | 
		
		
			| References: | 
			  | 
		
		
			
			
				- Alexander LJ, Hayes G, Pearse MJ, Beattie CW, Stewart AF, et al.  Complete sequence of the bovine beta-lactoglobulin cDNA.  Nucleic Acids Res 1989;17(16):6739.
 
				- Roth-Walter F, Pacios LF, Gomez-Casado C, Hofstetter G, Roth GA, et al. The major cow milk allergen Bos d 5 manipulates T-helper cells depending on its load with siderophore-bound iron. PLoS One. 2014; 9(8): e104803.
 
				- Luyt D, Ball H, Makwana N, Green MR, Bravin K, et al. BSACI Guideline for the Diagnosis and Management of Cow's Milk Allergy. Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology. 2014.
 
				- Fiocchi A, Bouygue GR, Albarini M, Restani P.  Molecular diagnosis of cow’s milk allergy.  Curr Opin Allergy Clin Immunol. 2011 Jun;11(3):216-21.
 
				- Kuwata K, Hoshino M, Forge V, Era S, Batt CA, Goto Y. Solution structure and dynamics of bovine beta-lactoglobulin A. Protein Sci. 1999 Nov;8(11):2541-5.
 
			 
			 | 
		
	
		  
	    
		  | File Name | 
		  Size | 
		  Added | 
		  Link | 
		
		
				    | NA-BD5_CoA | 
			  221.79KB | 
			  23/03/2015 | 
			  Download | 
			
						  
			    | Natural Bos d 5 Certificate of Analysis | 
			  
							
	  
	  
	    
                         
         
                                
          
          
            
                        - Product Code: NA-BD5-1
 
                        - Availability: In Stock
 
          
                    
                    
            
       
            Related Products
      
                        Tags:
                 milk allergen,
                         food allergen,
                         bos d 5,
                         β-Lactoglobulin,
                         milk,