Recombinant Der p 2 (RP-DP2A-1)

Description
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Allergen:	rDer p 2 (Dermatophagoides pteronyssinus allergen 2.0101), house dust mite
Unit:	250µg
Source:	P. pastoris
Mol. Wt:	14kD
Purification:	Purified from Pichia pastoris culture supernatant by multi- step chromatography. Purity on silver stained SDS-PAGE > 95%. (See Panel)
Concentration:	See product insert.
Formulation:	Preservative-free and carrier-free in phosphate buffered saline, pH 7.4. Sterile filtered.
Storage:	Store at -20ºC
Notes:	(1) rDer p 2.0101 has a C-terminal 6xHis-tag. (2) rDer p 2.0101 is suitable for T-cell or other in vitro studies, but does not react in the Group 2 mite ELISA. (3) Not tested for endotoxin.
Product Resources:	Recombinant Der p 2 Certificate of Analysis
An InBio^TM product For Research Use Only: Not for Diagnostic or Therapeutic Use
References:
Heyman PW, Chapman MD, Fox J, Aalberse, RC, PlattsMills, TAE. Antigenic and structural analysis of the Group II allergens (Derp II and Der f II) from house dust mites (Dermatophagoides sp). J Allergy Clin Immunology 1989;83:1055-67. Mueller GA, Smith AM, Williams DC Jr., Hakkaart GAJ, Aalberse RC, Chapman MD, Rule, GS, Benjmin DC. Expression and secondary structure determination by NMR methods of the major house dust mite allergen Der p 2. J Biol Chem 1997;272:26893-8. Smith AM, Benjamin DC, Hozic N, Derewenda U, Smith WA, Thomas WR, Gafvelin G, van Hage-Hamsten M, Chapman MD. The molecular basis of antigenic cross-reactivity between the group 2 mite allergens. J Allergy Clin Immunol 2001;107:977-84. Mueller GA, Smith AM, Chapman MD, Rule GS, Benjamin DC. Hydrogen exchange nuclear magnetic resonance spectroscopy mapping of antibody epitopes on the house dust mite allergen Der p 2. J. Biol. Chem. 2001;276:9359-65.