LoTox™ Natural Can f 1 (LTN-CF1-1)

Allergen:	nCan f 1 (Canis familiaris allergen 1), dog
Unit:	1mg (supplied as 4 x 0.25mg aliquots)
Source:	dog hair
Mol. Wt:	19 kD
Purification:	Purified from dog extract by multi-step affinity chromatography. Purity approximately 95% by silver stained SDS-PAGE.
Concentration:	See Product Insert.
Formulation:	Preservative and carrier-free in endotoxin free phosphate buffered saline, pH 7.4. Filtered through 0.22µm filter.
Storage:	Store at -20ºC
Notes:	(1) Can f 1 belongs to the lipocalin protein family (2) A LoTox™ product, Endotoxin < 0.03 EU/µg.
PDB:
Product Resources:	LoTox™ Natural Can f 1 Certificate of Analysis
Allergens are provided for research and commercial use in vitro: not for human in vivo or therapeutic use.
References:
Konieczny A, Morgenstern JP, Bizinkauskas CB, Lilley CH, Brauer AW, Bond JF, et al. The major dog allergens, Can f 1 and Can f 2, are salivary lipocalin proteins: cloning and immunological characterization of the recombinant forms. Immunology 1997;92:577-86. Pomes A, Smith AM, Gregoire C, Vailes LD, Arruda LK, Chapman MD. Functional properties of cloned allergens from dust mite, cockroach, and cat- are they relevant to allergenicity? ACI International 2001;13:162-169.